Course Description

Course fee: $259

Developed with support from the International Society for Orthomolecular Medicine, this course incorporates classical theories of orthomolecular medicine, including Lingus Pauling, Carl Pfeiffer, and Abram Hoffer’s groundbreaking contributions, in the context of modern psychiatry. We address, in particular, the micronutrient deficiencies, toxic neurochemical aggregations, systemic inflammation, and other etiologic factors in the treatment of schizophrenia and psychosis.

Course registration fee subsidized by the International Society for Orthomolecular Medicine.



1. Schizophrenia in Perspective

The first module shows the genetic and epigenetic influence on presentation of symptoms of schizophrenia/psychosis, revealing the illness to be an accumulation of innate and acquired biochemical deficiencies. We introduce a new integrative care model for schizophrenia that targets both the brain and body, environmental toxins, and other therapies.

2. A History of Orthomolecular Medicine

Module 2 offers a history of orthomolecular medicine and its pioneers, seguing into an examination of the use of niacin, vitamin C, and NAC in the treatment of schizophrenia.

3. Mastering Balance: Vitamin Deficiencies & Dependencies

This module is devoted to showing the association between several micronutrients—B vitamins (folate, B6 and B12), vitamin D, and zinc—and the presentation of symptoms of psychosis.

4. Inflammation, Gluten, and Dairy

Module 4 takes a deep dive into food hypersensitivities (allergies, intolerances, reactions) that exacerbate psychosis, as well as environmental, biochemical, and genetic factors that contribute to oxidative stress.  We will review biomarkers of inflammatory status and their associations with psychiatric disorders. The pathophysiology and therapeutic repercussions of celiac disease will be elucidated, bringing to the forefront of discussion the long-established link between diet and mental health. The module will conclude with a review of the gut-brain axis, the role of gut microbiota in neurologic health, and the implications of gut dysbiosis as they pertain to integrative treatment strategies for schizophrenia.

5. Orthomolecular Models for the Treatment of Schizophrenia

This module examines the prominent theories informing functional medicine approaches to psychosis. Providing an overview of the macronutrient deficiencies (such as dietary lipids and amino acids) that can present as psychosis, we conclude with an objective assessment of the efficacy of non-drug treatment options for this disease.

Learning Objectives:

Upon completion of this course, participants will be able to:

  • Identify the key genetic, nutritional, metabolic, and environmental causes of schizophrenia and psychosis
  • Understand orthomolecular medicine and its contributions to medical science
  • Know the micronutrient deficiencies, food allergens, gut dysbiosis, and macronutrient deficiencies that exacerbate psychosis and schizophrenia
  • Learn how to run and read diagnostic tests in the evaluation of patients’ symptoms
  • Describe the essential tenets and clinical implications of Horrobin’s Neurodevelopmental Hypothesis and the Phospholipid Hypothesis
  • Employ a functional medicine approach for better patient outcomes at your clinic or practice


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Other Educational Tools You May Like

Light on Schizophrenia: Revealing Causes and Solutions from an Orthomolecular Perspective

This book lays out the causes and contributors to schizophrenia from an orthomolecular perspective, along with solutions to address nutrient deficiencies, nutrient dependencies, and environmental toxins such as heavy metals. This book contains expertise from Dr. Hoffer’s 57 years of experience and success in treating schizophrenia, along with valuable new contributions from James Greenblatt, MD.

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