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Functional & Integrative Medicine for Depression

A Course by James Greenblatt, MD

Course Description

Price: $340
CME Credits: 5.0
CE Credits: 3.0

Over four modules, clinicians of all specialties will become adept in identifying and assessing the biologic abnormalities—nutritional, genetic, metabolic, and environmental factors—that underlie the diagnosis of depression in numerous patients. Employing a model of functional medicine, you will learn the diagnostic tests you should be running on patients, the role key nutrients play in maintaining neurologic health, and biologic treatment protocols that can be easily incorporated into your practice.

Learning Objectives

Upon completion of this course, students will be able to:

  • Identify the genetic, nutritional, metabolic, and environmental causes of depression
  • Describe the role of inflammation in the “depressogenic” process, along with dietary factors in the presentation of depression symptoms
  • Substantiate the physiologic associations between diet and depression
  • Identify the biologic pathways by which the acute and chronic physiologic ramifications of malnutrition and trauma influence suicidality in eating disorder populations
  • Analyze the impact of gut microbiota, macro and micronutrient deficiencies, and genetic variants of the MTHFR gene in the production of folates on depression
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Modules

1. A Biologic Model of Depression

In Module 1, Dr. Greenblatt explains functional and integrative medicine treatment protocols for depression, along with the broader polypharmaceutical crisis as it pertains to this clinical diagnosis. In particular, we review biochemical individuality and key biomarkers of “depressogenic” processes—genetics, inflammation, and dysbiosis, namely. Lastly, Dr. Greenblatt will describe integrative interventions to rebalance abnormalities, and elucidate our best practices in the assessment and treatment of depression.

2. Macronutrients: Proteins, Fats, and Carbohydrates

For Module 2, Dr. Greenblatt will take you on a deep dive into nutritional causes of depression and the incorporation of dietary interventions in your practice. Among other topics, students will find information on the role amino acids play in neurological health and how to prescribe free-form amino acids to patients, explore the link between essential fatty acids (EFAs), cholesterol, and lipids and depression, and unravel connections between depression and sugar consumption.

 

3. Micronutrients: Minerals

While in Module 2 Dr. Greenblatt demonstrated the connection between macronutrients and depression, in Module 2 he examines minerals, such as lithium, iron, magnesium, zinc, and copper for their role in brain function and neurologic health. He explores the physical and cognitive ramifications of a mineral deficiency or excess, along with the intrinsic and exogenous factors that impact mineral absorption, metabolism, and bioavailability as they relate to symptoms of depression. Lastly, he will review clinical tests for assessing mineral status in patients, along with recommendations for supplements to rectify micronutrient imbalances.

4. Micronutrients: Vitamins

In the final module, Dr. Greenblatt offers an overview of vitamins—B vitamins, vitamin D, and folates—exploring how they rebalance and influence the transmission and synthesis of neurons, cell receptor activation, and neuroendocrine responses. Variants of the MTHFR gene and effects on folate metabolism will be examined, along with guidelines for testing for vitamin deficiencies, achieving repletion, interpreting the results, and treating with key supplements.

Accreditation Information

Please click to expand each section and view accreditation information.

• CME Information

DURATION OF ACTIVITY
April 4, 2022 through April 3, 2024

ACCREDITATION STATEMENT
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of MedicusCME and Comprehensive Psychiatric Resources, Inc.  MedicusCME is accredited by the ACCME to provide continuing medical education for physicians.

DESIGNATION STATEMENT
MedicusCME designates this live activity for a maximum of 5.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

OVERVIEW
Over four modules, clinicians of all specialties will become adept in identifying and assessing the biologic abnormalities—nutritional, genetic, metabolic, and environmental factors—that underlie the diagnosis of depression in numerous patients. Employing a model of functional medicine, you will learn the diagnostic tests you should be running on patients, the role key nutrients play in maintaining neurologic health, and biologic treatment protocols that can be easily incorporated into your practice.

LEARNING OBJECTIVES

  • Identify the genetic, nutritional, metabolic, and environmental causes of depression
  • Describe the role of inflammation in the “depressogenic” process, along with dietary factors in the presentation of depression symptoms
  • Substantiate the physiologic associations between diet and depression
  • Identify the biologic pathways by which the acute and chronic physiologic ramifications of malnutrition and trauma influence suicidality in eating disorder populations
  • Analyze the impact of gut microbiota, macro and micronutrient deficiencies, and genetic variants of the MTHFR gene in the production of folates on depression

HOW TO CLAIM CREDIT
In order to receive AMA PRA Category 1 credit™, participants must do the following:

  • Read the learning objectives and faculty disclosures

  • Participate in the activity, review course content and learning strategies, resources and support materials provided

  • Complete the post-test and activity evaluation

  • Achieve a score of 80% or higher on the post-test

PLANNER
Mariela Podolski, MD
Podolski Psychiatry
Adult/Child and Adolescent Psychiatry
West Hartford, Connecticut

Walden Behavioral Care
Director of Child and Adolescent Psychiatry

Eating Disorder Consultant
Department of Corrections, Connecticut

Eating Disorder Consultant
DHMAS/Connecticut Valley Hospital, Connecticut

FACULTY
James Greenblatt, MD
Chief Medical Officer and Vice President of Medical Services
Walden Behavioral Care, Waltham, Massachusetts

Assistant Clinical Professor of Psychiatry
Tufts University School of Medicine
Boston, Massachusetts

DISCLOSURE OF FINANCIAL RELATIONSHIPS
MedicusCME requires instructors, planners, managers, and others in control of educational content to disclose all their financial relationships with ineligible companies over the previous 24 months. All identified financial relationships are thoroughly vetted and mitigated according to MedicusCME policy.

The faculty reported the following relevant financial relationships with Accreditation Council for Continuing Medical Education (ACCME)-defined ineligible entities related to the educational content of this CE activity.

James Greenblatt, MD has disclosed financial relationships with Fullscripts for an affiliate relationship and with Atrium Health/Pure Encapsulations and Jaymac Pharmaceuticals for participating on their Speakers Boards.

Any relevant financial relationships listed for planners or content contributors have been mitigated according to MedicusCME policies. MedicusCME planners and managers have no relevant financial relationships with ineligible companies to disclose.

ACKNOWLEDGEMENTS
This activity is not supported by funds from an ACCME-defined ineligible company.

HIPPA COMPLIANCE ATTESTATION
In accordance with the Health Insurance Portability and Accountability Act (HIPAA), this educational activity, especially when utilizing patient cases for learning demonstration, will not include individually identifiable health information.

DISCLOSURE OF UNLABELED USE
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration (FDA). The planners of this activity do not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

• CE Information

The CE Company is approved by the American Psychological Association to sponsor continuing education for psychologists. The CE Company maintains responsibility for this program and its content.

Course Level: Introductory
CE Instructions

This online program provides CE training and coursework. Accreditation requires the completion of a post-test. A passing grade of at least 75% must be met on this test in order to obtain certification. Instructions for certification will be provided upon completing the course in full.

Learning Objectives

Upon completion of this course, participants will be able to:

  1. Identify the genetic, nutritional, metabolic, and environmental causes of depression
  2. Describe the role of inflammation in the “depressogenic” process, along with dietary factors in the presentation of depression symptoms
  3. Substantiate the physiologic associations between diet and depression
  4. Discuss the acute and chronic physiologic ramifications of malnutrition and trauma, and identify biologic pathways by which these factors influence suicidality in eating disorder populations
  5. Discuss the impact of gut microbiota, macro and micronutrient deficiencies, and genetic variants of the MTHFR gene in the production of folates on depression
Instructor Bio

A pioneer in the field of integrative medicine, James M. Greenblatt, MD, has treated patients since 1988. After receiving his medical degree and completing his psychiatry residency at George Washington University, Dr. Greenblatt completed a fellowship in child and adolescent psychiatry at Johns Hopkins Medical School. He currently serves as the Chief Medical Officer at Walden Behavioral Care in Waltham, MA, and serves as an Assistant Clinical Professor of Psychiatry at Tufts University School of Medicine and Dartmouth College Geisel School of Medicine. Dr. Greenblatt has lectured internationally on the scientific evidence for nutritional interventions in psychiatry and mental illness. He is the author of seven books, including Finally Focused: The Breakthrough Natural Treatment Plan for ADHD. He is the founder of Psychiatry Redefined, an educational platform offering continuing online education, programs, and fellowships on functional and nutritional psychiatry for mental illness.

Conflict of Interest

The course instructor, James Greenblatt, M.D., is a consultant for Pure Encapsulations and owner of Psychiatry Redefined. He is also a key opinion leader for Fullscript. No assistance or financial compensation of any kind was provided by any outside commercial interest or entity in the development or preparation of this course.

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