This course offers practitioners a functional medicine model for the reduction and elimination of side-effects in patients taking psychotropic drugs. Registrants will be provided with an overview of pharmaceutical use in mainstream psychiatry, and the unprecedented steps some patients are now taking in order to get themselves off medication. A rationale for the implementation of a slow taper, secondary to an integrative assessment per THE ZEEEBRA approach, will be presented as a protocol for discontinuation and the elimination of withdrawal effects. Thereafter, nutritional and herbal interventions for the amelioration of medication-induced weight gain and sexual dysfunction will be reviewed. Gene variants associated with medication-induced weight gain will be discussed, and the clinical utility of gene testing for minimizing weight-related side-effects will be elucidated. Finally, tardive dyskinesia (TD) will be explored: biologic factors linked to its pathogenesis, mainstream treatment options, and the demonstrated superiority of integrative approaches for symptom resolution. Nutritional interventions with a proven track record of success in eliminating TD will be introduced, along with Dr. Greenblatt’s recommendations for dosing and titration. The course will conclude with an open-minded discussion about the role medications can and should play in today’s functional medicine practice, and a clarification of psychiatry’s most fundamental objectives in addressing mental illness safely, effectively, and ethically.